Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream.

By T.A. Syed, Z.A. Qureshi, S.M. Ali, S Ahmad and S.A. Ahmad.

"The prevalence of onychomycosis, a superficial fungal infection that destroys the entire nail unit, is rising, with no satisfactory cure. The objective of this randomized, double-blind, placebo-controlled study was to examine the clinical efficacy and tolerability of 2% butenafine hydrochloride and 5% Melaleuca alternifolia oil incorporated in a cream to manage toenail onychomycosis in a cohort...after 16 weeks, 80% of patients using medicated cream were cured, as opposed to none in the placebo group."

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