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Glucosamine Sulfate Caplets (90 count)



Product Description

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BENEFICIAL EFFECTS: Stimulates the manufacture of substances necessary for proper joint function and stimulates joint repair*

FOOD SOURCE: There are no food sources of glucosamine. Commercially available sources of glucosamine are derived from chitin, the specially processed exoskeleton of shrimp, lobster, and crab.

RECOMMENDATION DOSAGE: One caplet three times a day

PRODUCT DESCRIPTION: Each caplet contains:Glucosamine Sulfate 500 mg.Vitamin C 20 mg

LEGAL STATUS: Dietary supplement in accordance with Dietary Supplement Health and Education Act (1994).

Conforms to USP XXIII disintegration requirements Detailed human studies on glucosamine sulfate show an absorption rate as high as 98 percent.

Comparison of Glucosamine Preparations:

  Activity

Glucosamine Sulfate

 NAG

Glucosamine Hydrochochoride

Active intestinal transport

Yes

No

Yes

Detailed absorption studies

Yes

No

Yes

Detailed clinical studies

Yes

No

No

Contains sulfur molecule

Yes

No

No

Long history of use

Yes

No

No

Murray. M.T., Encyclopedia of Nutritional Supplements 1996

 

STRUCTURE/FUNCTION STATEMENT

  As some people age, they lose the ability to manufacture sufficient levels of glucosamine. The results is that    cartilage loses the ability to act as a shock absorber. The weight– bearing joints, like knees and hips, as well as the joints of the hands, are those most often affected. In affected joints, there may be a great deal of cartilage destruction followed by hardening and formation of large bone spurs in the joints margins Pain, deformity, and limitation of motion in the joint: results. 1 Glucosamine Sulfate’s beneficial effects are straightforward it stimulates the manufacture of substances necessary for the proper joint function and is responsible for stimulating joint repair. 2

GLUCOSAMINE SULFATE VERSUS CARTILAGE EXTRACTS

If you are trying to restore cartilage and joint structures, it is best to use glucosamine sulfate rather than chondroitin or shark cartilage. This is the case because of the improved absorption and utilization of glucosamine sulfate. The absorption rate for chondrotin sulfate is estimated to be between 0 and 8 percent. 3 In contrast, detailed pharmacokinetic studies indicate that after glucosamine sulfate is absorbed, it is preferentially taken up by cartilage and other joint structures where it stimulates the manufacture of chondroitin sulfate and other mucopolysaccharides

KNEES: The supplement glucosamine can keep your knees more limber and combat osteoarthritis. Researchers in Belgium found that osteoarthritis patients who took 1,500 mg of glucosamine daily had none of the knee-cartilage deterioration that patients taking a placebo suffered. Varicose veins can be erased through a painless, less-than-45-minute procedure called radio-frequency closure. Radio-frequency energy enters the vein wall, causing it to shrink and seal. Cost: $3,000

SIDE EFFECTS:

Glucosamine sulfate has an excellent safety record in animal and human studies and many experts recommend that it be considered as the nutrient of choice for prolonged use in joints function and repair. 4 Side effects are generally limited to light to moderate gastrointestinal symptoms, including stomach upset, heartburn, diarrhea, nausea, and indigestion. Glucosamine sulfate is extremely well tolerated and no allergic reactions have been reported.

 

1Setnikar,I., et al, Pharmacokinetics of Glucosamine in the Dog and Man, Arzneim Forsch 36 (4), 729-735, 1986

2 Setnikar, I et al, Pharmacokinetics of Glucosamine in Man, Arzeim Forch 43 (10), 1109-1113, 1993

3 Morrison, M., Therapeutic Applications of Chondroitin-4– Sulfate, Appraisal of Biologic Properties, Folia Angiol 25, 225-232, 1977

4 Setnikar, I., et al, Effects of Glucosamine Sulfate Studied in Animal Models, Armeim Forsch 41,542-545, 1991




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